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School of Medicine Pathology
Hossein Salimnia, Ph.D.

Hossein Salimnia, Ph.D.

hsalimni@dmc.org

313-745-4609

Hossein Salimnia, Ph.D.

Office address

Microbiology, Room 3E-7,
University Health Center,
4201 St. Antoine,
Detroit, MI 48201

Academic title

Professor

Administrative title

Technical Director of Microbiology Division at Detroit Medical Center University Laboratories

Education training

Ph.D. (1998): Laval University, Quebec, Canada

Postdoctoral Fellowship
1998-2000:    University of Ottawa, Ontario, Canada
2000-2003:    University of Rochester Medical Center, New York, NY, USA
 

Recent publications

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

  1. Cyrus Talebpour, Fereshteh Fani, Marc Quellet, Marilynn Fairfax, Houshang Alamdari, Hossein Salimnia. Identification and mitigation of blood’s interference with the antimicrobial activity of AgNbO3 particles. PLos One. Accepted June 6, 2025. In press. PONE-D-24-47006R2
  2. S. Kiran Koya , Michelle A. Brusatori , Sally Yurgelevic , Changhe Huang , Jake DeMeulemeester , Danielle Percefull , Hossein Salimnia , and Gregory W. Auner. Dec 2024. Rapid identification of Candida auris by Raman Spectroscopy combined with Deep learning. Journal of Raman Spectroscopy, First published: 26 December 2024, https://doi.org/10.1002/jrs.6763
  3. Cyrus Talebpour, Fereshteh Fani, Marc Ouellette, Marilynn Fairfax , Houshang Alamdari , Hossein Salimnia. Identification and mitigation of blood’s interference with the antimicrobial activity of AgNbO3 particles. PLoS One, 2025 Jun 24;20(6)
  4. Omar A, Asmar BI, Ang JY, Salimina H, Thomas R, Abdel-Haq N. Risk Factors for Infections Caused by Extended-Spectrum Beta-Lactamase Producing and Carbapenem-Resistant Enterobacterales in Pediatric Critical Care Settings: A Case-Control Study. Pediatr Infect Dis J 2025 May 1;44(5):422-427.
  5. Fereshteh Fani, Cyrus Talebpour, Philippe Leprohon, Hossein Salimnia, Houshang Alamdari and Marc Ouellette. 2024. Mode of action of silver-based perovskite against Gram negative bacteria. Microbiology spectrum. January 2025 Volume 13 Issue 1
  6. Talebpour C, Fani F, Salimnia H, Ouellette M, Alamdari H. Growth dynamics of Escherichia coli cells on a surface having AgNbO3 antimicrobial particles. PLoS One. August 19, 2024. https://doi.org/10.1371/journal.pone.0305315
  7. Talebpour C, Fani F, Laliberté-Riverin S, Vaidya R, Salimnia H, Alamdari H, Ouellette M. Long-Term Prevention of Arthroplasty Infections via Incorporation of Activated AgNbO3 Nanoparticles in PMMA Bone Cement. ACS Appl Bio Mater. 2024 Jun 17;7(6):4039-4050. doi: 10.1021/acsabm.4c00373. Epub 2024 Jun 3. PMID: 38830835.
  8. Keri VC, Topulli MV, Deol A, Uberti J, Salimnia H, Chandrasekar PH. False-Positive Human Immunodeficiency Virus Nucleic Acid Amplification Test After Chimeric Antigen Receptor T-Cell Therapy With Ciltacabtagene Autoleucel. Open Forum Infect Dis. 2023 Dec 11;11(1):ofad633. doi: 10.1093/ofid/ofad633. PMID: 38288349; PMCID: PMC10822836.
  9. Grewal M, Srivastava R, Ang JY, Salimnia H, Jain A. Unique presentation of late-onset Pneumocystis pneumonia in a pediatric kidney transplant recipient. Pediatr Transplant. 2023 Sep;27(6):e14576. doi: 10.1111/petr.14576. Epub 2023 Jul 13. PMID: 37448256.
  10. Alrayes T, Wait A, Spencer P, Merolla DM, Lampe K, Salimnia H, Kannikeswaran N. Features of an Atypical RSV Surge During the COVID-19 Pandemic. Clin Pediatr (Phila). 2023 May; 62(4):265-268.
  11. Harbir S Arora, Humera Khan, Haider Ailumerab, Girija Natarajan, Kathleen Meert, Hossein Salimnia, Rudolph Valentini, Ronald Thomas, Lynn Semproch, Basim I Asmar, Eric J McGrath. A tale of two intensive care units (ICUs): Baseline Staphylococcus aureus colonization and mupirocin susceptibility in neonatal and pediatric patients requiring intensive care Infect Control Hosp Epidemiol 23 March, 2023. 44(3): 447-452
  12. Holger DJ, Kunz Coyne AJ, Zhao JJ, Sandhu A, Salimnia H, Rybak MJ. Novel Combination Therapy for Extensively Drug-Resistant Acinetobacter baumannii Necrotizing Pneumonia Complicated by Empyema: A Case Report. Open Forum Infect Dis. 2022 Mar 5;9(4)
  13. Cyrus Talebpour, Fereshteh Fani, Marc Ouellette, Hossein Salimnia, and Houshang Alamdari. "Nondegradable Antimicrobial Silver-Based Perovskite" ACS sustainable chemistry & engineering vol. 10, no. 15 (April 03, 2022)
  14. Nahed Abdel-Haq, Basim I. Asmar. Jocelyn Y. Ang, Girija Natarajan, Marilynn Fairfax, Hossein Salimnia. Central line-associated blood stream infection (CLABSI) due to Candida sojae in an infant with short bowel syndrome: The first human case report. ID Cases. Volume 29, July 02, 2022,
  15. El Zein S, Chehab O, Kanj A, Akrawe S, Alkassis S, Mishra T, Shatta M, El-Hor N, Salimnia H, Chandrasekar P. SARS-CoV-2 infection: Initial viral load (iVL) predicts severity of illness/outcome, and declining trend of iVL in hospitalized patients corresponds with slowing of the pandemic. PLoS One. 2021 Sep 16;16(9)
  16. Rodrigues JA, Cha W, Mosci RE,Mukherjee S, Newton DW, Lephart P, Salimnia H, Khalife W, Rudrik JT, Manning SD. Epidemiologic Associations Vary Between Tetracycline and Fluoroquinolone Resistant Campylobacter jejuni Infections. Front Public Health. 2021 Jun 28;9:672473.
  17. Wolk DM, Young S, Whitfield NN, Reid JL, Thornberg A, Carroll KC, Buchan BW, Davis TE, Salimnia H. A Multicenter Clinical Study To Demonstrate the Diagnostic Accuracy of the GenMark Dx ePlex Blood Culture Identification Gram-Negative Panel. J Clin Microbiol. 2021 Aug 18;59(9):e0248420. doi: 10.1128/JCM.02484-20. Epub 2021 Aug 18. PMID: 34232066; PMCID: PMC8373019.
  18. Sarvepalli SS, Cruz ABV, Chopra T, Salimnia H, Chandrasekar P. Striking absence of "usual suspects" during the winter of the coronavirus disease 2019 (COVID-19) pandemic 2020-2021. Infect Control Hosp Epidemiol. 2021 Dec;42(12)
  19. Ang JY, Kannikeswaran N, Parker K, McGrath E, Abdel-Haq N, Arora H, Lua JL, Thomas R, Salimnia H, Chopra T, Tran T, Asmar B. COVID-19 among Minority Children in Detroit, Michigan during the Early National Surge of the Pandemic. Glob Pediatr Health. 2021 May 31;8
  20. Salimnia H, Meyer MP, Mitchell R, Fairfax MR, Gundel A, Guru N, Chopra T. A laboratory model demonstrating the protective effects of surgical masks, face shields, and a combination of both in a speaking simulation. Am J Infect Control. 2021 Apr;49(4):409-415.
  21. Eke UA, Fairfax MR, Mitchell R, Taylor M, Salimnia H. Staphylococcus pettenkoferi-positive Blood cultures in Hospitalized Patients in a Multi-site Tertiary Center. Diagn Microbiol Infect Dis. 2021 Apr;99(4)
  22. Salimnia H, Mitchell R, Gundel A, Cambell A, Gammou F, Chopra T, Fairfax M. Pooling samples: a testing option for SARS-CoV-2 during a supply shortage. Diagn Microbiol Infect Dis. 2021 Jan;99(1)
  23. Hansen, Z., W. Cha, B. Nohomovich, D. Newton, P. Lephart, H. Salimnia, W. Khalife, A. Shade, J.T. Rudrik, S.D. Manning. Comparing gut resistome composition among patients with acute Campylobacter infections and healthy family members. Sci Rep. 2021. Nov 16, ;11(1):22368   
  24. Cwengros LN, Mynatt RP, Timbrook TT, Mitchell R, Salimnia H, Lephart P, Pogue JM. Minimizing Time to Optimal Antimicrobial Therapy for Enterobacteriaceae Bloodstream Infections: A Retrospective, Hypothetical Application of Predictive Scoring Tools vs Rapid Diagnostics Tests. Open Forum Infect Dis. 2020 Jul 2;7(8)
  25. Sandhu A, Tillotson G, Polistico J, Salimnia H, Cranis M, Moshos J, Cullen L, Jabbo L, Diebel L, Chopra T. Clostridioides difficile in COVID-19 Patients, Detroit, Michigan, USA, March-April 2020. Emerg Infect Dis. 2020 Sep;26(9)
  26. Spruit JL, Knight T, Sweeney C, Salimnia H, Savaşan S. Clostridium difficile infection in a children's hospital with specific patterns among pediatric oncology and hematopoietic stem cell transplantation populations. Pediatr Hematol Oncol. 2020 Apr;37(3):211-222.
  27. Salimnia H, Veltman J, Chandrasekar PH, Pogue JM, Mynatt R, Salimnia T, Marshall SH, Hujer AM, Bonomo RA. Carbapenem-Susceptible Klebsiella pneumoniae and Escherichia coli Isolates Carrying a Truncated KPC Carbapenemase: a Challenge for Rapid Molecular Diagnostics. J Clin Microbiol. 2020 Feb 24;58(3)
  28. Mashock MJ, Faron ML, Carroll KC, Dang C, Lewis S, Salimnia H, Lephart P, Loo VG, Schmitt BH, Young S, Buchan BW, Ledeboer NA. A Multicenter Study of the Revogene C. difficile System for Detection of the Toxin B Gene from Unformed Stool Specimens. J Clin Microbiol. 2020 Jan 28;58(2)
  29. D Banerjee  , J Michael  , B Schmitt  , H Salimnia  , N Mhaissen, D M Goldfarb  , P Lachance , M L Faron  , T Aufderheide , N Ledeboer  , A Weissfeld  , R Selvarangan. Multicenter clinical evaluation of Revogene® Strep A molecular assay for detection of Streptococcus pyogenes from throat swab specimens. J Clin Microbiol . 2020 Jun 24;58(7)
  30. Knight T, Gupte A, Dulay K, Mitchell R, Salimnia H, Wang ZJ. 2020. Evaluation of an Empiric Antibiotic Regimen in Pediatric Oncology Patients Presenting with Fever Does Not Reveal the Emergence of Antibiotic Resistance Over a 12-Year Period. Pediatr Hematol Oncol Journal. Volume 5, Issue 3, September 2020, Pages 80-88

Research interests

Multi site clinical trials, evaluation of new diagnostic platforms, Molecular diagnosis of infectious diseases, multiplex real-time PCR, rapid detection/identification of pathogenic bacteria, fungi and viruses, antibiotic resistance, Raman spectroscopy

Representative accomplishments

Salimnia, H, Moore EC, Crane LR, MacArthur RD and Fairfax MR. Discordance between Viral Loads determined by Roche COBAS AMPLICOR Human Immunodeficiency Virus Type 1 Monitor (Version 1.5) Standard and Ultrasensitive Assays Caused by Freezing Patient Plasma in Centrifuged Beckton-Dickinson Vacutainer Brand Plasma Preparation Tubes. J Clin Microbiol. 2005 September; 43 (9): 4635-39

Publications

  1. Wolk, D. M., Young, S., Whitfield, N. N., Reid, J. L., Thornberg, A., Carroll, K. C., Buchan, B. W., Davis, T. E., & Salimnia, H. (2021). A multicenter clinical study to demonstrate the diagnostic accuracy of the genmark dx eplex blood culture identification gram-negative panel. Journal of clinical microbiology, Sept 2021, 59(9), [e02484-20]. https://doi.org/10.1128/JCM.02484-20
  2. Jocelyn Y. Ang, MD1,2,3 , Nirupama Kannikeswaran, Katherine Parker,, Eric McGrath, Nahed Abdel-Haq, Harbir Arora, Jorge L. Lua, Ronald Thomas, Hossein Salimnia, Teena Chopra, Tommy Tran, and Basim Asmar.2021. COVID-19 among Minority Children in Detroit, Michigan during the Early National Surge of the Pandemic Glob Pediatr Health. 2021 May 31;8:2333794X211022710. doi: 10.1177/2333794X211022710. eCollection 2021.
  3. Siri S. Sarvepalli , Angela Beatriz V. Cruz , Teena Chopra , Hossein Salimnia , Andrew Davidek 3, Maureen Taylor , Daale Maue, Pranatharthi Chandrasekar. Striking Absence of “Usual Suspects” during the Winter of COVID-19 Pandemic 2020-2021. Infect Control Hosp Epidemiol. 2021 Jun 24 : 1–2. Published online 2021 Jun 24. doi: 10.1017/ice.2021.303
  4. Jose A. Rodrigues 1 , Wonhee Cha1†, Rebekah E. Mosci 1 , Sanjana Mukherjee1† , Duane W. Newton2†, Paul Lephart 2 , Hossein Salimnia3,4, Walid Khalife5 , James T. Rudrik 6 and Shannon D. Manning. Epidemiologic associations vary between tetracycline and fluoroquinolone resistant Campylobacter jejuni infections
    Front. Public Health, 28 June 2021
  5. Uzoamaka A Eke, Marilynn R. Fairfax, Robert Mitchell, Maureen Taylor, Hossein Salimnia. Staphylococcus pettenkoferi-positive Blood cultures in Hospitalized Patients in a Multi-site Tertiary Center. Diagn Microbiol Infect Dis. 2021 Apr;99(4):115284. doi: 10.1016/j.diagmicrobio.2020.115284. Epub 2020 Dec 5
  6. Minimizing Time to Optimal Antimicrobial Therapy for Enterobacteriaceae Bloodstream Infections: A Retrospective, Hypothetical Application of Predictive Scoring Tools vs Rapid Diagnostics Tests Laura N. Cwengros, 1 Ryan P. Mynatt, 2 Tristan T. Timbrook, 3 Robert Mitchell, 4 Hossein Salimnia, 4,5 Paul Lephart, 6 and Jason M. Pogue7 Open Forum Infectious Diseases, Volume 7, Issue 8, August 2020, ofaa278, https://doi.org/10.1093/ofid/ofaa278
  7. Hossein Salimnia, Robert Mitchell, Angela Gundel, Alicia Cambell, Fadi Gammou, Teena Chopra, and Marilynn Fairfax. Pooling samples: a testing option for SARS-CoV-2 during a supply shortage. Diagn Microbiol Infect Dis. 2021 Jan; 99(1): 115205. Published online 2020 Sep 11. doi: 10.1016/j.diagmicrobio.2020.115205
  8. Knight T, Gupte A, Dulay K, Mitchell R, Salimnia H, Wang ZJ. 2020. Evaluation of an Empiric Antibiotic Regimen in Pediatric Oncology Patients Presenting with Fever Does Not Reveal the Emergence of Antibiotic Resistance Over a 12-Year Period. Pediatr Hematol Oncol Journal. Volume 5, Issue 3, September 2020, Pages 80-88
  9. Avnish Sandhu, Glenn Tillotson, Jordan Polistico, Hossein Salimnia, Mara Cranis, Judy Moshos, Lori Cullen, Lavina Jabbo, Lawrence Diebel, and Teena Chopra.2020. Clostridioides difficile in COVID-19 Patients, Detroit, Michigan, USA, Emerging Infect. Dis. Volume 26, Number 9—September 2020.
  10. Laura N. Cwengros, Ryan P. Mynatt, Tristan T. Timbrook, Robert Mitchell, Hossein Salimnia, Paul Lephart, Jason M. Pogue,. Minimizing time to optimal antimicrobial therapy for Enterobacteriaceae bloodstream infections: A retrospective, hypothetical application of predictive scoring tools versus rapid diagnostics tests. Open Forum Infectious Diseases, ofaa278, https://doi.org/10.1093/ofid/ofaa278 Published: 02 July 2020.
     

Courses taught by Hossein Salimnia, Ph.D.

Fall 2026 (future)

Winter Term 2026 (current)

Fall Term 2025

Winter Term 2025

Fall Term 2024

Winter Term 2024

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