School of Medicine

Wayne State University School of Medicine


Margarita Palutke, M.D.
Director of Hematology/Hematopathology and Hematopathology Fellowship
Medical Director of Core Hematology
4201 St. Antoine
Detroit, MI 48201
(313) 993-0486
Clinical and anatomic pathology, hemaopathology, lymphomas, leukemia and laboratory automation
Administrative Contact
Brenda Batts
(313) 577-1102
Research Interests

Molecular and Immunophenotypic markers in lymphoma and leukemia

Clinical Interests

  • Consultative expertise in all hematologic malignancies as well as non malignant disorders of bone marrow, peripheral bloods and lymphoid tissues
  • Flow cytometry
  • Histocompatibility (established and served as director, Histocompatibility Laboratory, 1970 -1991).

Research interest is in the field of Immunophenotypic characterization of T- and B-cell malignancies. My laboratory in flow cytometry is one of the earliest laboratories that introduced flow cytometric analysis in the State of Michigan. Currently, my laboratory is focusing in defining molecular markers in different hematologic malignancies with the aim for more specific therapies.


Wayne State University School of Medicine, Detroit, Michigan, USA

Wayne State University School of Medicine, Pathology Residency
Detroit, Michigan, USA

Wayne State University School of Medicine and Veterans Administration Hospital
Hematopathology Fellowship, two-year research associate track

  • Zhang H, Salimnia H., Bentley G, Weimin L, Phillips M, Feldman G, Palutke M: Two morphologically and immunophenotypically distinct cell populations within a composite lymphoma arise from a common precursor, J of Hematophathology 4:165-174, 2011
  • Bayerl MG, Bentley G, Bellow CM, Leoncini L, Ehmann CW, Palutke M: Follicular lymphoma with Reed Sternberg like cells represent large B cell transformation as demonstrated by microdissection and molecular analysis. Am J Clin Path 122:858-864.2004
  • Bayerl, MG, Rakozy C, Mohamed AN, Vo T, Long M, Eilender D, Palutke: Blastic Natural Killer Cell Lymphoma Leukemia: A Report of Seven Cases. Am J Clin Pathol, 117:41-50, 2002.
  • Rakozy CK, Mohamed AN, Vo TD, Khatib G, Long PM, Eilander D, Palutke M, CD56+CD4+ Lymphomas and Leukemias are morphologically and clinically diverse, Am J Clin Pathol. 116:168-176, 2001
  • Palutke M, Johnson R, 1996, Total Hematology Automation: A modular approach to a completely integrated clinical laboratory. Laboratory Automation News 1:8-13,1996.
  • Palutke M, Tabaczka PM, Kukuruga D, Kantor N, A method for measuring lymphocyte proliferation in mixed lymphocyte cultures using a nuclear proliferation antigen, KI-67, and flow cytometry. Am J Clin Pathol. 91:41-47,1989