School of Medicine

Wayne State University School of Medicine


William Kupsky
Departmental Faculty Development Liaison
Department of Pathology
Harper Hospital
3990 John R
Detroit, MI 48201
(313) 745-8555
Neuropathology, brain tumors, neuromuscular pathology, developmental neuropathology, and pathology of epilepsy
Administrative Contact
Brenda Batts
Phone: (313) 577-1102
Research Interests

Cancer, Pathology of Epilepsy, Neuromuscular Pathology, and Developmental Neuropathology


Dr. Kupsky has been actively involved in collaborative research and plays a key role in the epilepsy program, clinical brain tumor program, and clinical neuromuscular program.


M.D. (1978): Harvard Medical School, Boston, MA, USA


  • 1984: College of Physicians and Surgeons of Columbia University, New York, NY, USA, in Anatomic Pathology and Neuropathology


  • Board-certification: American Board of Pathology, Anatomic Pathology and Neuropathology
Medical Education Responsibilities

Undergraduate Program
Lectures of Pathobiology and Pathophysiology

Neuropathology for Pathology, Neurology, and Neurosurgery Residents; Currently Program Director in Pathology; Autopsy Pathology

Various ancillary health sciences (Pathology Assistants, etc.)


1. Kamson DO, Juhász C, Buth A, Kupsky WJ, Barger GR, Chakraborty PK, Muzik O, Mittal S. Tryptophan PET in pretreatment delineation of newly-diagnosed gliomas: MRI and histopathologic correlates. J Neurooncol. 2013 Jan 9. [Epub ahead of print].

2. Juhász C, Chugani DC, Barger GR, Kupsky WJ, Chakraborty PK, Muzik O, Mittal S. Quantitative PET imaging of tryptophan accumulation in gliomas and remote cortex:correlation with tumor proliferative activity. Clin Nucl Med. 2012 Sep;37(9):838-42.

3. Jacques SM, Kupsky WJ, Giorgadze T, Qureshi F. Fetal central nervous system injury in third trimester stillbirth: a clinicopathologic study of 63 cases. Pediatr Dev Pathol. 2012 Sep-Oct;15(5):375-84. doi: 10.2350/12-01-1137-OA.1. Epub 2012 Jul 31.

4. Acsadi G, Moore SA, Chéron A, Delalande O, Bennett L, Kupsky W, El-Baba M, Le Rumeur E, Hubert JF. Novel mutation in spectrin-like repeat 1 of dystrophin central domain causes protein misfolding and mild Becker muscular dystrophy. J Biol Chem. 2012 May 25;287(22):18153-62. doi: 10.1074/jbc.M111.284521. Epub 2012 Mar 27.

5. Alkonyi B, Mittal S, Zitron I, Chugani DC, Kupsky WJ, Muzik O, Chugani HT,Sood S, Juhász C. Increased tryptophan transport in epileptogenicdysembryoplastic neuroepithelial tumors. J Neurooncol. 2012 Apr;107(2):365-72.

6. Nundkumar N, Mittal M, Kupsky WJ, Folbe A, Mittal S. Complete recovery of acute monocular visual loss following endoscopic resection of anterior clinoid mucocele: case report and review of the literature. J Neurol Sci. 2012 Jan 15;312(1-2):184-90.

7. Puntambekar P, Santhakumar S, Kupsky WJ, Tselis A, Mittal S. Primaryintracranial plasma cell granulomas presenting as malignant neoplasms. J Neurooncol. 2012 Jan;106(2):327-37.

8. Hattab EM, Martin SE, Al-Khatib SM, Kupsky WJ, Vance GH, Stohler RA, Czader M, Al-Abbadi MA. Most primary central nervous system diffuse large B cell lymphomas occurring in immunocompetent individuals belong to the non-germinal center subtype: a retrospective analysis of 31 cases. Mod Pathol 23:235-243, 2010.